ea0041gp36 | Bone & Calcium Homeostasis | ECE2016
Petryk Anna
, Polgreen Lynda E
, Brown Roland
, Marino Bradley S
, Gremmels David
, Shepard Charles
, Kelly Aaron S
, Miller Bradley S
, Rudser Kyle
, Kochilas Lazaros K
Background: Survivors with Fontan circulation suffer from chronic systemic hypoperfusion resulting in end-organ injury. Little is known about the effects of these hemodynamic perturbations on bone. We hypothesized that chronic Fontan circulation (>5 years after surgery) would be associated with bone deficits.Methods: Peripheral quantitative computed tomography (pQCT) was performed on 10 Fontan patients (seven males, 11.8±1.7 years) and 11 health...